Status:

COMPLETED

A Study of RO5093151 in Patients With Ocular Hypertension Or Open Angle Glaucoma

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Hypertension, Glaucoma, Open-Angle

Eligibility:

All Genders

21+ years

Phase:

PHASE2

Brief Summary

This randomized, double-blind, placebo-controlled, multi-center study will evaluate the safety and the effect of RO5093151 on intraocular pressure in patients with ocular hypertension or open angle gl...

Eligibility Criteria

Inclusion

  • Adult patients, at least 21 years of age, inclusive
  • Diagnosis of ocular hypertension or primary open angle glaucoma in at least one eye
  • Able to participate and willing to give informed consent

Exclusion

  • Presence of extreme narrow angle with complete or partial closure
  • Progressive retinal or optic nerve disease from any cause other than glaucoma
  • History or signs of penetrating ocular trauma
  • Uncontrolled hypertension
  • Clinically significant abnormalities in laboratory test results
  • Positive test results on hepatitis B, hepatitis C, or HIV 1 and 2
  • Kidney disease or dysfunction

Key Trial Info

Start Date :

December 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2012

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT01493271

Start Date

December 1 2011

End Date

November 1 2012

Last Update

November 2 2016

Active Locations (12)

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Page 1 of 3 (12 locations)

1

Morrow, Georgia, United States, 30260

2

High Point, North Carolina, United States, 27262

3

Mt. Pleasant, South Carolina, United States, 29464

4

Sofia, Bulgaria, 1517