Status:

UNKNOWN

Pathophysiology of Diverticular Disease

Lead Sponsor:

Maastricht University Medical Center

Conditions:

Colonic Diverticula

Diverticulitis

Eligibility:

All Genders

50-75 years

Brief Summary

Colonic diverticular disease is a highly prevalent condition in Western populations. The prevalence increases age-dependently from 5% at 40 years to 65% by the age of 85 years (1-3). The majority rema...

Eligibility Criteria

Inclusion

  • Age ≥ 50 years and ≤ 75 years
  • Scheduled for colonoscopy
  • Written informed consent
  • Patient group: The presence of diverticulosis, diagnosed during the scheduled colonoscopy
  • Control group: During the scheduled colonoscopy, diverticulosis or other
  • gastrointestinal and liver diseases are absent. In other words, the
  • colonoscopy is qualified as a 'normal' colonoscopy.

Exclusion

  • Age \< 18 years
  • Presence of gastrointestinal and liver diseases, such as inflammatory bowel disease.
  • Use of NSAID's and proton pump inhibitors, during the 5-day time period prior to endoscopy.
  • Alcohol intake above 14 consumptions per week for males and 7 consumption per week for females
  • (Sub)total colectomy or hemicolectomy.
  • Refusal to participate in this study

Key Trial Info

Start Date :

January 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2014

Estimated Enrollment :

210 Patients enrolled

Trial Details

Trial ID

NCT01493349

Start Date

January 1 2012

End Date

October 1 2014

Last Update

January 5 2012

Active Locations (1)

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1

Maastricht University Medical Center

Maastricht, Limburg, Netherlands, 6202 AZ