Status:

UNKNOWN

Serum Proteomics Analysis for Sepsis

Lead Sponsor:

Chinese PLA General Hospital

Conditions:

SIRS

Sepsis

Eligibility:

All Genders

18+ years

Brief Summary

Serum proteomics is a very useful tool to identify various disease. The purpose of the present study was to find differential proteins among patient with normal, SIRS, sepsis, severe sepsis, death and...

Eligibility Criteria

Inclusion

  • Male and female aged 18 years old and over;
  • clinically confirmed infection;
  • fulfilled at least two criteria of systemic inflammatory response syndrome
  • (a) core temperature higher than 38 °C or lower than 36 °C
  • (b)respiratory rate above 20/min, or PCO2 below 32 mmHg
  • (c) pulse rate above 90/min, and
  • (d) white blood cell count greater than 12,000/μl or lower than \< 4,000/μl or less than 10% of bands.

Exclusion

  • younger than 18 years of age;
  • acquired immunodeficiency syndrome;
  • reduced polymorphonuclear granulocyte counts (\< 500 μL-1);
  • died within 24h after admission into the ICU, or refused to participate in the study, or declined treatment during the period of observation.

Key Trial Info

Start Date :

May 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2012

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT01493466

Start Date

May 1 2010

End Date

March 1 2012

Last Update

December 16 2011

Active Locations (1)

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Chinese PLA General Hospital

Beijin, Beijing Municipality, China, 100853