Status:
UNKNOWN
The Clinical Trial on the Use of Umbilical Cord Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis
Lead Sponsor:
General Hospital of Chinese Armed Police Forces
Conditions:
Amyotrophic Lateral Sclerosis
Eligibility:
All Genders
20-65 years
Phase:
PHASE2
Brief Summary
Patients with Amyotrophic Lateral Sclerosis (ALS) typically endure a progressive paralysis due to the continued loss of motoneurons that leads them to death in less than 5 years. No treatment has chan...
Detailed Description
A total of 30 diagnosed ALS patients. The patients would got these symptoms such as gait difficulty and tremor, hand incoordination or speech difficulties.
Eligibility Criteria
Inclusion
- Diagnose established following the World Federation of Neurology criteria
- More than 6 and less than 36 months of evolution of the disease
- Medullar onset of the disease
- More than 20 and less than 65 years old
- Forced Vital Capacity equal or superior to 50%
- Total time of oxygen saturation \<90% inferior to 2% of the sleeping time
- Signed informed consent
Exclusion
- Neurological or psychiatric concomitant disease
- Need of parenteral or enteral nutrition through percutaneous endoscopic gastrostomy or nasogastric tube
- Concomitant systemic disease
- Treatment with corticosteroids, immunoglobulins or immunosuppressors during the last 12 months
- Inclusion in other clinical trials
- Unability to understand the informed consent
Key Trial Info
Start Date :
March 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 1 2015
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01494480
Start Date
March 1 2012
End Date
April 1 2015
Last Update
June 20 2012
Active Locations (1)
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1
Yihua An
Beijing, China