Status:
COMPLETED
Antifungal Prophylaxis in Intensive Care Unit (ICU) Patients
Lead Sponsor:
Policlinico Hospital
Conditions:
Fungal Prophylaxis
Candida Infection
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Purpose. Oral chemoprophylaxis has been advocated to reduce the incidence of Candida colonization and infection. However, Candida prophylaxis in intensive care unit (ICU) is still a matter of debate. ...
Detailed Description
Multiple-site testing for fungi included: tracheal secretions, pharingael swab, stomach contents, rectal swab, groin skin fold swab, urine, and blood. These tests will be performed in each patient at ...
Eligibility Criteria
Inclusion
- surgical patients admitted to our ICU older than 18 years of age and expected to require invasive mechanical ventilation for more than 48 h.
Exclusion
- pregnancy,
- proven Candida infection,
- prophylactic or curative antifungal treatment within the last 2 months,
- contraindication to oral drug administration,
- known allergy to nystatin or its derivatives, and prior inclusion in the study
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT01495039
Start Date
November 1 2008
End Date
February 1 2010
Last Update
April 5 2017
Active Locations (1)
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1
Intensive care Unit, Policlinico Hospital Bari
Bari, Italy, Italy, 70100