Status:
COMPLETED
Effect of Woodsmoke on Vascular Function
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
Umeå University
NHS Lothian
Conditions:
Vascular Function
Eligibility:
MALE
18-35 years
Phase:
NA
Brief Summary
Exposure to air pollution is a well established risk factor for the development of heart disease. Firefighters are exposed to excess air pollution in the form of wood smoke during the extinguishing of...
Eligibility Criteria
Inclusion
- Non-smoking healthy male firefighters or volunteers
Exclusion
- Current smoker or regular users of snus
- History of lung or ischaemic heart disease
- Malignant arrhythmia
- Systolic blood pressure \>190mmHg or \<100mmHg
- Renal or hepatic dysfunction
- Previous history of blood dyscrasia
- Unable to tolerate the supine position
- Blood donation within the last 3 months
- Recent respiratory tract infection within the past 4 weeks
- Routine medication including aspirin and NSAIDs
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2014
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT01495325
Start Date
September 1 2011
End Date
August 1 2014
Last Update
June 21 2021
Active Locations (1)
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1
Umeå University
Umeå, Västerbotten County, Sweden, SE-901 85