Status:
COMPLETED
A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
ALS Association
ALS Finding a Cure
Conditions:
Amyotrophic Lateral Sclerosis
Nervous System Diseases
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to collect biofluid samples for the banking and usage in ALS research. Through comparison of these samples, the researchers hope to learn more about the underlying cause o...
Detailed Description
The purpose of the research study is to collect blood samples and cerebrospinal fluid (CSF) from people with amyotrophic lateral sclerosis (ALS). These samples will be collected approximately every 4 ...
Eligibility Criteria
Inclusion
- Age 18 or older
- Diagnosis of suspected, possible, probable or definite ALS according to El Escorial Criteria
- Vital capacity (VC) at least 50 percent predicted
- Able to undergo multiple lumbar punctures
Exclusion
- Abnormal CSF pressure or intracranial/intraspinal tumors
- Use of anticoagulant medication that cannot be safely withheld
- Bleeding disorders
- This is a partial listing.
Key Trial Info
Start Date :
November 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2016
Estimated Enrollment :
139 Patients enrolled
Trial Details
Trial ID
NCT01495390
Start Date
November 1 2011
End Date
December 31 2016
Last Update
May 30 2017
Active Locations (6)
Enter a location and click search to find clinical trials sorted by distance.
1
Barrow Neurological Institute
Phoenix, Arizona, United States, 85013
2
Mayo Clinic Jacksonville
Jacksonville, Florida, United States, 32224
3
Emory University
Atlanta, Georgia, United States, 30322
4
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114