Status:
COMPLETED
High-frequency Oscillatory Ventilation (HFOV) in Preterm Infants With Severe Respiratory Distress Syndrome (RDS)
Lead Sponsor:
Zhengzhou Children's Hospital, China
Conditions:
Respiratory Distress Syndrome
Eligibility:
All Genders
Up to 24 years
Phase:
PHASE2
Brief Summary
Respiratory distress syndrome (RDS) is common in preterm infants born at less than 32 weeks gestation; surfactant and mechanical ventilation have been the standard treatment. However, despite advances...
Detailed Description
All patients were monitored including blood pressure, heart rate, oxygen saturation, ventilator settings, and arterial blood gases pre- or during mechanical ventilation. PaO2/FIO2 was calculated. Afte...
Eligibility Criteria
Inclusion
- Preterm infants admitted to the NICU with gestational age \<32 weeks, birth weight \<1500g and less than 24 hours of age
- Who developed RDS requiring mechanical ventilation
- Presented a partial pressure of oxygen (PaO2): fraction of inspired oxygen (FIO2) ratio \<200
- Radiograph criteria of severe RDS
Exclusion
- Infants with genetic metabolic diseases
- Congenital abnormalities
- Pneumothorax
- Grade III-IV intracranial hemorrhage
Key Trial Info
Start Date :
June 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2011
Estimated Enrollment :
360 Patients enrolled
Trial Details
Trial ID
NCT01496508
Start Date
June 1 2007
End Date
June 1 2011
Last Update
December 21 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Zhengzhou Children's Hospital
Zhengzhou, Henan, China, 450003