Status:
COMPLETED
Memory Training Intervention for Breast Cancer Survivors
Lead Sponsor:
Indiana University
Conditions:
Breast Cancer
Eligibility:
FEMALE
40+ years
Phase:
NA
Brief Summary
This is a randomized controlled trial to evaluate the ACTIVE memory training intervention and ACTIVE speed of processing training to waitlist, no-contact control conditions. Specific aims and hypothes...
Detailed Description
Memory deficits are a prevalent, bothersome, and potentially debilitating symptom for millions of breast cancer survivors (BCS). Evidence-based treatment is difficult because there has been little int...
Eligibility Criteria
Inclusion
- female gender (breast cancer is rare in men);
- self-reported memory impairment and desire for treatment (to focus on BCS in greatest need);
- first diagnosis of non-metastatic breast cancer (to control for multiple treatments or brain metastases in women with recurrent or metastatic disease);
- ≥ 1 year post-treatment including surgery, radiation, and/or chemotherapy (reduce confounding factors related to acute effects of treatment);32
- age ≥ 40 years (our prior studies indicate approximately 75% of BCS meet this criterion and reduce sample variability);
- post-menopausal (majority are post-menopausal at diagnosis and reduce sample variability); and
- able to read, write, understand, and speak English (to ensure informed consent).
Exclusion
- Women will be excluded if they have other co-morbidities or deficits that would sufficiently impair performance or inhibit cognitive training including:
- substantial cognitive decline (score \< 24 on the Mini Mental State Exam (MMSE);33
- history of stroke, encephalitis, traumatic brain injury, brain surgery, dementia, Alzheimer disease, or Parkinson disease;
- cranial radiation therapy or intrathecal therapy;
- current active major depression or substance abuse or history of bipolar disorder, psychosis, schizophrenia, or learning disability;
- history of or current other cancer except for basal cell skin cancer; or
- receiving other cognitive training (to avoid exposure to other training).
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
88 Patients enrolled
Trial Details
Trial ID
NCT01497015
Start Date
September 1 2008
End Date
December 1 2012
Last Update
February 23 2023
Active Locations (1)
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1
Indiana University
Indianapolis, Indiana, United States, 46202