Status:

UNKNOWN

Safety and Performance of the Zeus CC Stent for the Treatment of Iliac Occlusive Disease

Lead Sponsor:

be Medical

Conditions:

Peripheral Artery Disease

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to evaluate safety and performance of the balloon-expandable Zeus CC (Rontis AG) stent for the treatment of Trans-Atlantic Inter-Society Consensus (TASC) A, B, C and D ili...

Eligibility Criteria

Inclusion

  • Patient is older than 18 years
  • Patient must sign a written informed consent form that is approved by the ethics committee prior to index-procedure
  • Patient must be compliant with all follow-up visits
  • Patient suffers from intermittent claudication (Rutherford 1-3) or critical limb ischemia (Rutherford 4 and 5)
  • Patient's life expectancy is more than 2 years
  • Patient has iliac atherosclerotic de novo lesion(s) type A, B, C \& D according to TASC-II classification
  • Target vessel diameter is between 5 and 9 mm
  • Target lesion has a baseline diameter stenosis of more than 50%
  • Patient has sufficient infra-inguinal run-off with at least a patent common femoral artery and deep femoral artery (both \<50% stenosis)

Exclusion

  • Patient has a life expectancy of less than 2 years
  • Patient is refusing to be compliant with all follow-up visits
  • Patient suffers from acute limb ischemia, defined as any sudden decrease in limb perfusion causing a potential threat to limb viability.
  • Patient is intolerant to anticoagulant or antiplatelet therapy such as aspirin, heparin, clopidogrel or ticlopidine drug therapy
  • Patient has already been treated with a stent in the ipsilateral target vessel
  • Patient suffered tissue loss in the target extremities, defined as Rutherford 6
  • Patient is already enrolled in this or another investigational device study
  • Patient had a coronary intervention within the last 60 days before enrolment into this study or there is a planned coronary intervention within 60 days of enrolment into this study
  • Use of alternative therapy (e.g. atherectomy, cutting balloon, laser, radiation therapy) as part of the index-procedure
  • Any planned surgical intervention within 30 days of the index-procedure
  • Patient has an abdominal aortic aneurysm that is likely to require repair within the next 2 years.
  • Patient has no sufficient infra-inguinal run-off (\>50% stenosis). Patient inclusion is only possible if revascularization (endovascular or surgical) is performed in the same procedure with a peroperative angiographic control yielding \<30% stenosis.
  • Target lesion is a restenotic lesion.
  • Target lesion is adjacent an aneurysm.
  • Target vessel perforation with documented contrast extravasation during index-procedure prior to stent placement.

Key Trial Info

Start Date :

December 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2015

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT01499329

Start Date

December 1 2011

End Date

December 1 2015

Last Update

July 16 2015

Active Locations (1)

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AZ Sint Jan Bruges

Bruges, Belgium