Status:

COMPLETED

Minimally Invasive Groin Dissection for Melanoma

Lead Sponsor:

Mayo Clinic

Conditions:

Melanoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this this study is to determine if a structured educational training program is successful in teaching surgeons a new operative technique. It will then be determined if this new operati...

Detailed Description

This study is a multi-center, Phase 1 clinical trial to determine the safety and feasibility of minimally invasive inguinal lymph node dissection for patients with melanoma. Licensed surgeons who have...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Malignant melanoma present in an inguinal nodal basin requiring superficial inguinal lymph node dissection.
  • Plan for superficial inguinal dissection alone or combined superficial inguinal and deep pelvic node dissection is acceptable.
  • Clinical or radiographic evidence of superficial inguinal lymph node disease or a prior positive single lymph node biopsy of the superficial inguinal basin as an indication for superficial inguinal lymph node disease is acceptable.
  • Patients must be Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1 and be healthy enough to undergo a general anesthetic (no epidural or spinal anesthetics).
  • Female patients of child bearing age must have a negative pregnancy test, be surgically sterile or post-menopausal greater than 1 year.
  • Patients must be able to return to surgical facility for 30 and/or 90 day (+/- 20 days) for follow-up appointment.
  • Exclusion Criteria:
  • Prior ipsilateral superficial inguinal lymph node dissection
  • Invasion or ulceration of inguinal nodal disease into the overlying skin
  • Prior radiation therapy to the same regional nodal basin.

Exclusion

    Key Trial Info

    Start Date :

    June 1 2012

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 1 2015

    Estimated Enrollment :

    88 Patients enrolled

    Trial Details

    Trial ID

    NCT01500304

    Start Date

    June 1 2012

    End Date

    December 1 2015

    Last Update

    March 23 2018

    Active Locations (11)

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    Page 1 of 3 (11 locations)

    1

    Mayo Clinic in Arizona

    Scottsdale, Arizona, United States, 85259

    2

    John Wayne Cancer Institute

    Santa Monica, California, United States, 90404

    3

    Mayo Clinic in Florida

    Jacksonville, Florida, United States, 32224

    4

    H. Lee Moffitt Cancer Center and Research Institute

    Tampa, Florida, United States, 33612