Status:
COMPLETED
The Effects of Intra-articular Injection of Mesenchymal Stem Cells in Knee Joint Osteoarthritis
Lead Sponsor:
Royan Institute
Conditions:
Osteoarthritis
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Osteoarthritis of the knee is one of the most common causes of disability among elderly. As the disease progresses the cartilage become frustrated, surrounding bone react to become thicker and inflamm...
Detailed Description
This is single center, randomized, triple blind phase II clinical study. Patients will be divided into two groups of case and control. All subjects will undergo bone marrow aspiration. Mesenchymal ste...
Eligibility Criteria
Inclusion
- Osteoarthritis diagnosed by MRI
Exclusion
- Pregnancy or lactating
- Positive tests for HIV, HCV, HBV
- Active neurologic disorder
- End organ damage
- Uncontrolled endocrine disorder
Key Trial Info
Start Date :
October 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2015
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01504464
Start Date
October 1 2012
End Date
October 1 2015
Last Update
May 17 2016
Active Locations (1)
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1
Royan Institute
Tehran, Iran