Status:
UNKNOWN
Chromoendoscopy for Dysplasia Detection in Chronic Inflammatory Bowel Disease
Lead Sponsor:
Karolinska University Hospital
Conditions:
Ulcerative Colitis
Crohn's Colitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Patients with longstanding ulcerative colitis or crohn's disease in the large bowel have an increased risk of developing cancer. The purpose of this study is to determine if visualizing of the mucosa ...
Detailed Description
Background: Patients with ulcerative colitis and Crohn's colitis are at increased risk of colon cancer. The usefulness of chromoendoscopy is debated. Previous studies are either based on magnifying en...
Eligibility Criteria
Inclusion
- Patients with ulcerative colitis or Crohn's colitis satisfying criteria for surveillance colonoscopy:
- Ulcerative colitis, extensive \> 8 years OR Crohn's colitis involving ≥ 1/3 of colon/rectum
- history of PSC or
- history of previous dysplasia on colon biopsies or
- family history of colon cancer in first degree relative
Exclusion
- Patients who decline to participate
- Unable to give informed consent
- Increased risk of bleeding (i.e. Warfarin, bleeding disorders, Clopidogrel)
Key Trial Info
Start Date :
February 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 4 2019
Estimated Enrollment :
304 Patients enrolled
Trial Details
Trial ID
NCT01505842
Start Date
February 1 2011
End Date
April 4 2019
Last Update
March 6 2019
Active Locations (1)
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1
Karoliniska University Hospital, Dept. of Gastroenterology
Stockholm, Sweden, 17176