Status:
COMPLETED
Optimizing the Temperature for Embryo Culture in In Vitro Fertilization
Lead Sponsor:
Reproductive Medicine Associates of New Jersey
Conditions:
Infertility
Eligibility:
FEMALE
18-41 years
Phase:
NA
Brief Summary
Many human and animal studies over the past 40 years have revealed that ovaries and Fallopian tubes have a lower temperature than core body temperature, especially around the time of ovulation and ear...
Eligibility Criteria
Inclusion
- No more than 1 prior failed cycle at RMA NJ facility; up to 2 prior failed cycles at another facility pending investigator review
- Female partner between 18 and 41 at onset of IVF cycle
- Normal day 3 FSH (\< or = 12) in RMA NJ laboratory
- Basal antral follicle count of at least 10
- Male partner with greater than 100,000 total motile spermatozoa per ejaculate (donor sperm is ok)
- BMI \< or = 32 kg/m2
Exclusion
- Diagnosis of chronic anovulation (cycles occuring typically less often than every 90 days)
- Use of testicular aspiration or biopsy procedures to obtain sperm
- Unevaluated ovarian mass or diagnosis of surgically-confirmed stage IV endometriosis
- Presence of hydrosalpinges that communicate with the uterine cavity
- History of endometrial insufficiency
- Any contraindication to undergoing IVF or gonadotropin stimulation
- Prior poor fertilization rate- less than 50% of mature eggs
- Prior poor blastulation rate- less than 10% of 2PNs (day 1 embryos)
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2014
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT01506089
Start Date
January 1 2012
End Date
July 1 2014
Last Update
March 26 2015
Active Locations (2)
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1
Reproductive Medicine Associates of New Jersey
Morristown, New Jersey, United States, 07960
2
Reproductive Medicine Associates of Pennsylvannia
Allentown, Pennsylvania, United States, 18104