Status:
COMPLETED
Double Push Acoustic Radiation Force (DP ARF) Ultrasound for Monitoring Degeneration in Duchenne Muscular Dystrophy
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborating Sponsors:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Muscular Dystrophy, Duchenne
Eligibility:
MALE
5-13 years
Brief Summary
This is a pilot clinical trial to assess the ability of a new ultrasound-based imaging method, Double-Push Acoustic Radiation Force (DP ARF) ultrasound, to monitor the progression of Duchenne muscular...
Detailed Description
Double Push Acoustic Radiation Force (DP ARF) imaging will be performed in 3 cohorts of up to 10 boys with DMD and in age-matched boys with no known neuromuscular disorders. The first DMD cohort will...
Eligibility Criteria
Inclusion
- Clinical diagnosis of Duchenne muscular dystrophy with clinical onset by age 5
- Ability to stand, alone or with assistance, at time of enrollment
- Ability to communicate with pertinent staff
- Ability to understand and comply with study requirements
- Ability to give informed consent.
Exclusion
- Confirmed diagnosis of other muscle disease
- Previous compartment syndrome
- Previous injury to selected limbs
- Previous vascular surgery to selected limbs
- History of a compressive neuropathy (e.g., sciatic, femoral or tibial palsy in leg)
- History of rhabdomyolysis
Key Trial Info
Start Date :
January 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 31 2020
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01506518
Start Date
January 1 2012
End Date
May 31 2020
Last Update
August 2 2021
Active Locations (1)
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1
The University of North Carolina at Chapel Hill Hospitals
Chapel Hill, North Carolina, United States, 27599