Status:
COMPLETED
The Impact of SCN9A Gene Polymorphism on Individual Pain Perception in the General Population
Lead Sponsor:
Xianwei Zhang
Conditions:
Pain
Surgery
Eligibility:
All Genders
20-70 years
Brief Summary
This study was conducted to explore whether the non-synonymous single-nucleotide polymorphisms in SCN9A gene can predict individual basal pain perception and postoperative pain intensity in the genera...
Detailed Description
Patients with the following diseases were excluded: known history of chronic pain, psychiatric diseases or communication disorders, diabetes mellitus, severe cardiovascular diseases, kidney or liver d...
Eligibility Criteria
Inclusion
- Aged 20-70 years
- Receiving elective upper abdominal surgery
- Anesthesiologists (ASA) physical status I or II
- Received PCA administration
- Agreed to participate the research
Exclusion
- History of chronic pain
- Psychiatric diseases
- Diabetes mellitus
- Severe cardiovascular diseases
- Kidney or liver diseases
- Alcohol or drug abuse
- Heavy smoker
- Pregnancy or at lactation period
- Refused PCA administration
- Disagree to participate to the research
Key Trial Info
Start Date :
January 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01507493
Start Date
January 1 2011
End Date
December 1 2012
Last Update
September 3 2014
Active Locations (1)
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1
Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430030