Status:
UNKNOWN
Calorie Restriction Retards the Aging Process
Lead Sponsor:
University of Chile
Conditions:
Obesity
Eligibility:
FEMALE
25-40 years
Phase:
NA
Brief Summary
Calorie restriction is the only experimental manipulation that prolongs longevity in experimental animals. The life prolonging effects of calorie restriction are related to a lower incidence of tumors...
Detailed Description
HYPOTHESIS: Calorie restriction delays the ageing process and thus telomere erosion, due to a reduction of oxidative stress, via expression modulation of uncoupling proteins and sirtuins. RETROSPECTI...
Eligibility Criteria
Inclusion
- overweight or obese premenopausal women aged 25 - 40 years
Exclusion
- diabetes,
- chronic diseases,
- extreme physical exercise,
- drugs affecting energy expenditure
Key Trial Info
Start Date :
May 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2013
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT01508091
Start Date
May 1 2012
End Date
June 1 2013
Last Update
October 23 2012
Active Locations (1)
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1
Clinica Alemana de Santiago
Santiago, Santiago Metropolitan, Chile