Status:

COMPLETED

Vitamin D3 Effects on Musculoskeletal Symptoms With Use of Aromatase Inhibitors

Lead Sponsor:

HealthPartners Institute

Collaborating Sponsors:

University of Minnesota

University of Southern California

Conditions:

Muscle Pain

Joint Pain

Eligibility:

FEMALE

18+ years

Phase:

PHASE2

Brief Summary

The Purpose of this study is to determine whether vitamin D3 supplements will decrease the muscle and bone pain that are reported by women who take Aromatase Inhibitors.

Detailed Description

This project will determine the efficacy of vitamin D3 supplements for reducing side effects of treatment with aromatase inhibitors in women with a history of breast cancer that have no evidence of cu...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years
  • Women with a history of stage I-IIIa invasive breast cancer
  • History of hormone-receptor positive cancer (either ER + or PR + or both)
  • Are prescribed and are taking anastrozole, letrozole or exemestane for at least one month and have at least 7 months of AI treatment remaining
  • Are experiencing AIMSS

Exclusion

  • Unable to read or understand English
  • History of psychiatric disability affecting informed consent or compliance with drug intake
  • Malabsorption syndrome or inability to take oral medication
  • Has less than 7 months of AI therapy remaining

Key Trial Info

Start Date :

March 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2015

Estimated Enrollment :

116 Patients enrolled

Trial Details

Trial ID

NCT01509079

Start Date

March 1 2012

End Date

March 1 2015

Last Update

June 18 2019

Active Locations (1)

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Park Nicollet Frauenshuh Cancer Center

Minneapolis, Minnesota, United States, 55416