Status:
TERMINATED
Vascular Dysfunction in Diabetes: Genes and Hormones
Lead Sponsor:
Brigham and Women's Hospital
Conditions:
Diabetes Mellitus
Eligibility:
All Genders
18-65 years
Brief Summary
The investigators are very excited that the National Institutes of Health are sponsoring us to investigate why patients with diabetes are more likely to develop high blood pressure, atherosclerosis (h...
Eligibility Criteria
Inclusion
- Type II Diabetes Mellitus
- Age between 18-65 years
- BMI \< 40
- In overall good health
Exclusion
- History of coronary atherosclerotic disease, MI, CVA, or significant peripheral vascular disease
- BMI \> 40
- Subjects with diastolic blood pressures greater than 100 mm Hg while on anti-hypertensive medications, or systolic blood pressures greater than 160 mm Hg while on anti-hypertensive medications will be excluded.
- Current alcohol or drug abuse
- Subjects taking other medications (except thyroid supplements, oral hyperglycemic agents and insulin) will be excluded
- Subjects who are on medications that cannot be discontinued such as anti-depressants, anti-seizure medications, etc that may interfere with salt and water handling will not be studied.
Key Trial Info
Start Date :
December 1 1999
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01511042
Start Date
December 1 1999
End Date
June 1 2020
Last Update
November 9 2022
Active Locations (1)
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1
Brigham and Women's Hospital- 221 Longwood Avenue
Boston, Massachusetts, United States, 02115