Status:

COMPLETED

Safety and Efficacy of Ibuprofen in Term Newborns With Patent Ductus Arteriosus (PDA)

Lead Sponsor:

Hormozgan University of Medical Sciences

Conditions:

Patent Ductus Arteriosus

Eligibility:

All Genders

20-28 years

Phase:

NA

Brief Summary

The aim of current study is to evaluate the efficacy and safety of oral Ibuprofen in term 20-28 days old newborn referred to Bandarabbas children' hospital in 2011.

Detailed Description

Patent Ductus Arteriosus (PDA) accounts for about 10% of Congenital Heart Disease. Surgical treatment in PDA is associated with higher rate of complication than pharmacologic treatment. Efficacy of Ib...

Eligibility Criteria

Inclusion

  • Term newborn (37 weeks of gestation or more)
  • Age between 20-28 days
  • confirmed diagnosis of PDA by echocardiography by pediatric cardiologist

Exclusion

  • Asphyxia
  • Hemorrhage
  • Platelet count \< 150000
  • renal or gastrointestinal malformations
  • associated congenital heart disease

Key Trial Info

Start Date :

January 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2012

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT01511887

Start Date

January 1 2011

End Date

January 1 2012

Last Update

January 20 2012

Active Locations (1)

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Hormozgan University of Medical Sciences

Bandar Abbas, Hormozgan, Iran, 097145-3388