Status:
COMPLETED
Post-Stroke Aphasia and Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Study
Lead Sponsor:
University of Alabama at Birmingham
Collaborating Sponsors:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions:
Aphasia
Stroke
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
In this study the investigators will examine the efficacy of navigated excitatory repetitive transcranial magnetic stimulation (nerTMS) for the treatment of post stroke aphasia. The investigators expe...
Detailed Description
Aphasia after stroke is associated with high mortality, significant motor impairment, and severe limitations in social participation. During the past decade, therapies administered by stroke teams hav...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- LMCA stroke as indicated by the presence of aphasia and MRI lesion in the LMCA distribution
- Moderate aphasia (Token Test score between 40th and 90th percentile)
- Fluency in English
- Provision of written informed consent by the patient and/or the next of kin
Exclusion
- Age less than 18 years
- Underlying degenerative or metabolic disorder or supervening medical illness
- Severe depression or other psychiatric disorder
- Positive pregnancy test in women of childbearing age
- Any contraindication to MRI/fMRI at 3T (i.e., intracranial metal implants, claustrophobia)
- Any contraindication to nerTMS (e.g., seizures or epilepsy)
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 20 2018
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT01512264
Start Date
January 1 2012
End Date
July 20 2018
Last Update
July 14 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Alabama at Birmingham
Birmingham, Alabama, United States, 35294