Status:
COMPLETED
Clinical Trial Based on the Use of Mesenchymal Stem Cells From Autologous Bone Marrow in Patients With Lumbar Intervertebral Degenerative Disc Disease
Lead Sponsor:
Red de Terapia Celular
Collaborating Sponsors:
Haematology Service,University Hospital of Salamanca, MªConsuelo del Cañizo Fernández-Roldán
Spanish National Health System
Conditions:
Intervertebral Disc Disease
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this trial is to test the effectiveness of the use of a new therapeutic strategy in treating patients with degenerative disc disease lumbar intervertebral fusion with instrumented poste...
Eligibility Criteria
Inclusion
- Clinical
- Box symptomatic (back pain and / or root) of lumbar degenerative disc disease monosegmental.
- Discopathy refractory to conservative treatment (drugs, physical therapy.)
- Evolution greater than or equal to 6 months. Radiological
- Discopathy radiation. Disc space narrowing, osteophytes, abnormal mobility, etc
- NMR: grades IV and V of Pfirman.
Exclusion
- Rejection of surgical treatment.
- Systemic inflammatory disease (spondylitis, rheumatoid arthritis etc), tumor or infection.
- Immunosuppressive treatment.
- Congenital or acquired anatomical abnormality that prevents the surgical procedure.
- Neuropsychiatric pathology, drug addiction, psychosis, severe personality disorder.
- High surgical risk (ASA\> IV), or contraindication to anesthesia.
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 4 2017
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT01513694
Start Date
January 1 2010
End Date
May 4 2017
Last Update
June 2 2017
Active Locations (1)
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1
Trauma Service. Hospital Universitario de Salamanca
Salamanca, Castille and León, Spain, 37007