Status:
COMPLETED
New Dual Therapy for Primary Treatment of Helicobacter Pylori Infection：a Pilot Study
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Functional Dyspepsia
Eligibility:
All Genders
18-70 years
Phase:
PHASE2
Brief Summary
The efficacy of traditional triple therapy has been decreased to such an unacceptable level as 70% in many areas. The study is based on the hypothesis: the most important factors which influence the e...
Detailed Description
The current recommended triple regimen for H. pylori treatment provides unacceptable low success rates because of high antibiotic resistance and poor compliance. Dual therapy had been used before and ...
Eligibility Criteria
Inclusion
- Patients aged from 18 to 70 years, who presented with upper gastrointestinal symptoms and endoscopically proven H. pylori-positive non-ulcer dyspepsia, were recruited into the study.
Exclusion
- patients with peptic ulcer,
- previous H. pylori eradication treatment,
- previous gastric surgery,
- pregnancy,
- lactation,
- major systemic diseases,
- receipt of anti-secretory therapy,
- antibiotics or bismuth in the preceding four weeks, or - allergy to any one of the medications in the regimen.
Key Trial Info
Start Date :
April 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01513785
Start Date
April 1 2011
End Date
January 1 2012
Last Update
January 20 2012
Active Locations (1)
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1
GI Division, Shanghai Jiao-Tong University School of Medicine Renji Hospital
Shanghai, Shanghai Municipality, China, 200001