Status:
COMPLETED
Effect of Curcumin on Lung Inflammation
Lead Sponsor:
Baylor College of Medicine
Collaborating Sponsors:
M.D. Anderson Cancer Center
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
Chronic obstructive pulmonary disease (COPD) and lung cancer are leading causes of death and health care use. Diffuse airways inflammation is seen in COPD and is thought to be the reason for deteriora...
Eligibility Criteria
Inclusion
- Age equal or more than 45 with moderate COPD: FEV1/FVC ratio less than 70 percent; post bronchodilator FEV1 less than 50 percent
- 20 pack year cigarette smoking
- Stable clinical course (symptoms/ medications) for 8 weeks
- Fixed address/Not planning to leave
- Being able to perform spirometry
- Able to understand and consent
Exclusion
- Other chronic respiratory diseases such as asthma, interstitial fibrosis, sarcoidosis
- Heart failure NYH III \& IV; symptomatic liver or renal failure
- Dementia or other neurocognitive deficit preventing completion of symptom diary
- Use of inhaled or systemic corticosteroids within 8 weeks of enrollment in the study
Key Trial Info
Start Date :
April 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2010
Estimated Enrollment :
57 Patients enrolled
Trial Details
Trial ID
NCT01514266
Start Date
April 1 2005
End Date
August 1 2010
Last Update
January 23 2012
Active Locations (1)
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1
VA Medical Center
Houston, Texas, United States, 77030