Status:
COMPLETED
Physical Exercise as an Additional Treatment for Alzheimer Disease
Lead Sponsor:
Universidade Federal do Rio de Janeiro
Collaborating Sponsors:
Rio de Janeiro State Research Supporting Foundation (FAPERJ)
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Conditions:
Alzheimer Disease
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The state of the art with regard to the neurodegenerative dementias, especially for Alzheimer´s disease (AD), is that their progression is still irreversible causing cognitive, motor, and behavioral i...
Detailed Description
* Design: Four-month controlled, randomized, and double-blind study. The patients will be recruited by trained psychiatrists from the Center for Alzheimer's disease in the Institute of Psychiatry of t...
Eligibility Criteria
Inclusion
- Diagnosis of Alzheimer Disease according to the National Institute of Neurological and Communicative Disorders and Stroke- Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) and National Institute of Neurological Disorders and Stroke- Association Internationale pour la Recherche et l' Enseignement en Neurosciences (NINDS-AIREN),respectively
- Mini-Mental State Examination (MMSE) score ≥ 15
- Clinical Dementia Rating (CDR) score 1
- Regular use of anticholinesterase drugs for at least six months
- Cardiologist's authorization
- At least six months without practicing physical exercises.
Exclusion
- Clinical depression or Cornell Scale ≥ 7
- Other types of dementia
- Physical limitation due to other pathologies or associated neurological disease
- Severe or uncontrolled arterial hypertension
- Marked visual and/or auditory deficit
- Incapacity to perform physical exercise due to neurological or neuromuscular impairments
- Illiteracy
- Less than six months of treatment at the outpatient unit.
Key Trial Info
Start Date :
February 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01515982
Start Date
February 1 2010
End Date
December 1 2013
Last Update
December 3 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Universidade Federal do Rio de Janeiro
Rio de Janeiro, Rio de Janeiro, Brazil