Status:

COMPLETED

Screening of Healthy Adults for Genetic Variations That Control Fatty Acid Processing

Lead Sponsor:

Wake Forest University Health Sciences

Collaborating Sponsors:

National Center for Complementary and Integrative Health (NCCIH)

Office of Dietary Supplements (ODS)

Conditions:

Healthy

Eligibility:

All Genders

21-65 years

Brief Summary

The purpose of this research study is to screen healthy African American and Caucasian persons for specific differences in genes that control how fats are processed in the body.

Detailed Description

Healthy African American and Caucasian persons will be screened for specific differences in genes that control how fats are processed in the body. Persons with the needed genotypes will be added to a ...

Eligibility Criteria

Inclusion

  • Be Caucasian or African American between 21-65 years of age
  • Be healthy and free of any major illness
  • Be a nonsmoker
  • Have an intact gallbladder
  • Have TG \< 150 and blood pressure less than 130/90
  • Must be willing to be re-contacted for future studies

Exclusion

  • Not have: myocardial infarction, vascular surgery or stroke within the past year
  • Not be taking niacin, more than 100 mg aspirin/day or montelukast allergy medications
  • BMI equal to or greater than 30 or less than 19
  • Fasting glucose greater than 125 mg/dl
  • Pregnancy

Key Trial Info

Start Date :

September 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 17 2019

Estimated Enrollment :

458 Patients enrolled

Trial Details

Trial ID

NCT01516125

Start Date

September 1 2011

End Date

April 17 2019

Last Update

November 30 2023

Active Locations (1)

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Wake Forest Health Sciences

Winston-Salem, North Carolina, United States, 27157