Status:
UNKNOWN
Immunology of Failing Metal-on-Metal Hip Replacement
Lead Sponsor:
University of East Anglia
Collaborating Sponsors:
Depuy, Inc.
Conditions:
Infection of Total Hip Joint Prosthesis
Implants
Eligibility:
All Genders
Brief Summary
Metal-on-metal total hip replacement (MoM THR) has been targeted at younger patients with anticipated long-term survival since the bearing surfaces wear less than the traditional metal-on-plastic (MoP...
Detailed Description
To characterize dendritic cell (DC) populations in MoM THR patients. Dendritic cells are cells that migrate from the circulating blood into tissues and mop up foreign material such as viruses with the...
Eligibility Criteria
Inclusion
- Patients who have undergone Ultima TPS THRs in Norwich
- Patients with a MoP THR under going revision.
- Patients undergoing primary hip replacement with osteoarthritis
- Patients with other MoM THRs undergoing revision
Exclusion
- Patients undergoing primary THR with rheumatoid arthritis or other inflammatory arthritides, or secondary to infection
Key Trial Info
Start Date :
January 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2015
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT01517737
Start Date
January 1 2012
End Date
January 1 2015
Last Update
February 9 2012
Active Locations (2)
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1
Norfolk and Norwich University Hospital NHS Trust
Norwich, Norfolk, United Kingdom, NR4 7UY
2
Norfolk and Norwich University Hospital
Norwich, Norfolk, United Kingdom, NR4 7UY