Status:

COMPLETED

Age-related Normative Values for the Octopus 900 Perimeter

Lead Sponsor:

University Hospital Tuebingen

Collaborating Sponsors:

Haag-Streit AG

Conditions:

Healthy

Eligibility:

All Genders

11-79 years

Phase:

NA

Brief Summary

The purpose of this study is to determine normal values of the visual field (VF), corrected for age- and reaction time (RT) using the Octopus 900 perimeter and semi-automated kinetic perimetry (SKP).

Eligibility Criteria

Inclusion

  • maximum spherical ametropia ± 6 Diopters (D)
  • maximum cylindrical ametropia ± 2 D
  • distant visual acuity ≥ 1.0 logMAR \[20/20\] for subjects up to 60 years, ≥ 0.8 logMAR \[20/25\] for subjects from 61-70 years, ≥ 0.63 logMAR \[20/30\] for subjects older than 70 years
  • isocoria, pupil diameter \> 3mm
  • intraocular pressure (air pulse tonometer) ≤ 21mmHg
  • normal anterior segments
  • ocular fundus: normal appearance of the cup to disc ratio (CDR) ≤ 0.5, interocular difference of CDR \< 0.3
  • normal macular region, vessels, and peripheral retinal examination (with undilated pupils).

Exclusion

  • amblyopia
  • strabismus
  • ocular motility disorder
  • diseases of the retina
  • glaucoma, glaucoma suspect
  • macular degeneration
  • IOP \> 21 mmHg
  • abnormal color vision test (ISPP - Ishihara and Standard Pseudoisochromatic Plates = SPP)
  • history or findings of other neuro-ophthalmological disease
  • relevant opacities of the central refractive media (cornea, lens, vitreous body)
  • use of miotic drugs
  • intraocular surgery (except uncomplicated cataract surgery, more than three months previous to testing)
  • kerato-refractive surgery (LASIK)
  • drugs influencing reaction time
  • drugs indicating severe general diseases (anti-diabetic pharmaceuticals and anti-hypertensive medication were allowed for subjects older than 70 years)
  • mental diseases (for example psychosis)
  • pregnancy, nursing
  • acute infections
  • heavy smoking (\>10 cigarettes /day)
  • alcohol abuse
  • diabetic retinopathy
  • coronary heart disease
  • stroke
  • migraine
  • Raynaud's syndrome
  • suspected lack of compliance

Key Trial Info

Start Date :

June 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2008

Estimated Enrollment :

86 Patients enrolled

Trial Details

Trial ID

NCT01518686

Start Date

June 1 2006

End Date

September 1 2008

Last Update

December 11 2013

Active Locations (1)

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Centre for Ophthalmology / Institute for Ophthalmic Research, University of Tübingen

Tübingen, Baden-Wurttemberg, Germany, 72076