Status:
COMPLETED
Orthostatic Dysregulation and Associated Gastrointestinal Dysfunction in Parkinson's Disease - Evolution
Lead Sponsor:
University of Zurich
Conditions:
Parkinson's Disease - Autonomic Dysregulation
Eligibility:
All Genders
50-70 years
Brief Summary
Symptoms of blood pressure dysregulation, impaired swallowing and digestion are common amongst parkinson patients. The overall aim of this study is to examine blood pressure regulation and esophageal ...
Eligibility Criteria
Inclusion
- Inclusion criteria: - informed, written \& formal consent for participation
- male/female subjects, aged 50-70 years
- PD patients (9 subjects each in Hoehn \& Yahr stage 1 \& 2)
- Exclusion criteria: - Antihypertensive treatment
- medication influencing gastrointestinal motility for at least the elimination half life of the drug
- medication interfering with blood-pressure regulation for at least the elimination half life of the drug
- significant systemic illness
- BMI \< 18 or \> 30kg/m2
- symptoms or a history of GI disease or surgery
- with any evidence of infectious disease
- evidence or history of drug or alcohol abuse
- diabetes mellitus
Exclusion
Key Trial Info
Start Date :
December 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2014
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT01518751
Start Date
December 1 2011
End Date
December 1 2014
Last Update
September 30 2015
Active Locations (1)
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1
University Hospital Zurich, Neurology
Zurich, Canton of Zurich, Switzerland, 8091