Status:

COMPLETED

Short Course, Single-dose PEG 3350 for Colonoscopy Prep in Children

Lead Sponsor:

Walter Reed National Military Medical Center

Conditions:

Colonoscopy

Eligibility:

All Genders

8-18 years

Phase:

NA

Brief Summary

The investigators propose to conduct a prospective study of a widely used bowel preparation regimen (polyethylene glycol 3350 + a sports drink) on pediatric patients who undergo a colonoscopy performe...

Detailed Description

Purpose: It is hoped that by determining acceptability, safety and efficacy of this widely used short course, single-dose bowel preparation regimen, pediatric gastroenterologist can have a standardize...

Eligibility Criteria

Inclusion

  • Male and female DEERS-eligible dependent military health care beneficiaries age 8 to 18 years old evaluated by Pediatric Gastroenterology service at WRAMC and are scheduled to undergo a colonoscopy between 1 Sep 2010 - 31 Dec 2011 and do not meet exclusion criteria.

Exclusion

  • Age less than 8 years or greater than 18 at time of procedure
  • Colonic surgery including hemicolectomy, colectomy, ileostomy, or multiple abdominal surgeries.
  • Oral aversion or other feeding disorder.
  • Inability to drink large amount of liquids.
  • Aspiration risk.
  • Renal disease or pre-cleanout electrolytes outside normal range.
  • Significant cardiovascular disease.
  • Allergy to food coloring or polyethylene glycol 3350.
  • Inpatient or emergency colonoscopy.
  • Current nasogastric tube in place.
  • Known Pregnancy. Urine pregnancy test will only be completed on day of colonoscopy for all females age 14 and older per current standard anesthesia protocols. There have been no known reported animal or human studies that report the fetal effects of using polyethylene glycol. Per FDA, it is labeled as a category C drug in pregnancy. However, two studies , have reported successful treatment of constipation during pregnancy using polyethylene glycol solutions and did not find any significant effects or safety issues

Key Trial Info

Start Date :

September 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2011

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT01518790

Start Date

September 1 2010

End Date

August 1 2011

Last Update

February 10 2016

Active Locations (1)

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Walter Reed National Military Medical Center

Bethesda, Maryland, United States, 20814