Status:
UNKNOWN
Effect of Intravitreal Bone Marrow Stem Cells on Ischemic Retinopathy
Lead Sponsor:
University of Sao Paulo
Conditions:
Ischemia
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
This study aims to evaluate the behavior of the intravitreal use of bone marrow derived stem cells in patients with ischemic retinopathy.
Detailed Description
Evaluate the effects on visual acuity, electroretinography, fluorescein angiography and optical coherence tomography in 30 patients with ischemic retinopathy, including diabetic retinopathy with sever...
Eligibility Criteria
Inclusion
- diagnosis of Ischemic Retinopathy
- Enlargement of foveal avascular zone-FAZ (ischaemia or capillary drop out of \>30% on Fluorescein retinography
- logarithm of minimum angle of resolution (logMAR) BCVA of 1.0 (Snellen equivalent, 20/200) or worse
- Able (in the Investigator's opinion) and willing to comply with all study requirements
Exclusion
- previous ocular surgery other than cataract
- presence of cataract or other media opacity that would influence ocular fundus documentation and adequate ERG and visual field evaluation
- other ophthalmic disease like glaucoma and uveitis
- previous history of blood disorders like leukemia
- known allergy to fluorescein or indocyanine green
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01518842
Start Date
September 1 2011
End Date
January 1 2020
Last Update
October 16 2018
Active Locations (1)
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1
Rubens Siqueira Research Center
São José do Rio Preto, São Paulo, Brazil, 15010-100