Status:
COMPLETED
Mechanical Ventilation With Neurally-Adjusted Ventilatory Assist in Patients With ARDS
Lead Sponsor:
University of Sao Paulo General Hospital
Collaborating Sponsors:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Conditions:
Acute Respiratory Distress Syndrome
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Neurally-Adjusted Ventilatory Assist (NAVA) is a ventilatory mode that uses the electrical activity of the diaphragm to control the mechanical ventilator, offering inspiratory assistance in proportion...
Detailed Description
Neurally Adjusted ventilatory-Assist(NAVA) is an assisted ventilatory mode that captures the electrical activity of the diaphragm and uses it to initiate and terminate the inspiratory phase, offering ...
Eligibility Criteria
Inclusion
- Mechanical ventilation for more than 24 hours;
- Diagnosis of ARDS
- Clinical indication of lung protective mechanical ventilation by the ICU team;
- Presence of active inspiratory efforts for more than 6 hours
Exclusion
- Patients under 18 years;
- Pregnant women;
- Trauma or burns of the face that hinder the passage of gastro-esophageal catheter;
- Nasal pathologies that prevent the progression of gastro-esophageal catheter;
- Ulcers of the esophagus or stomach;
- Documented esophageal varices;
- Tracheostomized patients;
- Instability of the chest wall or diaphragmatic injury;
- Hemodynamic instability, defined as the need to increase vasoactive drugs in the last two hours in order to maintain the mean arterial pressure above 60 mmHg).
Key Trial Info
Start Date :
October 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2015
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01519258
Start Date
October 1 2012
End Date
December 1 2015
Last Update
April 3 2019
Active Locations (1)
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1
University of Sao Paulo General Hospital
São Paulo, São Paulo, Brazil, 05403-010