Status:
UNKNOWN
Effect of an Oral Probiotic Tablet on Oral Bacteria and Clinical Measurements (ProBiora3)
Lead Sponsor:
Oragenics, Inc.
Collaborating Sponsors:
University of Washington
Conditions:
Oral Health
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
The purpose of this study is to determine if an oral probiotic tablet taken once a day for twelve weeks can decrease the numbers of bacteria that are associated with tooth decay and gum disease in a d...
Detailed Description
There are over 500 types of bacteria in the mouth. Most of these bacteria do not cause disease. However, some mouth bacteria can cause tooth decay and gum disease. The purpose of a probiotic tablet fo...
Eligibility Criteria
Inclusion
- minimum of 20 teeth, with only a few fillings
- good general health
- willing to use an appropriate method of birth control during the study
- measurable levels of Streptococcus mutans and one or more of the selected periodontal pathogens
Exclusion
- chronic or acute illness such as heart disease, diabetes, cancer, hepatitis (liver disease) or HIV positive
- radiation therapy or systemic cancer treatment (chemotherapy)
- require antibiotics for dental treatment
- pregnant or planning to become pregnant during the study period
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT01520974
Start Date
January 1 2012
Last Update
May 2 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Washington, Scool of Dentistry, Regional Clinical Dental Research Center
Seattle, Washington, United States, 98195