Status:

UNKNOWN

Effect of the Salbutamol on Mechanical Properties of Respiratory System

Lead Sponsor:

Rio de Janeiro State University

Collaborating Sponsors:

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Rio de Janeiro State Research Supporting Foundation (FAPERJ)

Conditions:

Smoking

Airway Obstruction

Eligibility:

All Genders

40+ years

Phase:

NA

Brief Summary

The aim of this study is to assess the bronchodilator response of salbutamol on respiratory mechanics of healthy individuals, smokers and COPD with varying degrees of airway obstruction.

Detailed Description

Clinical evaluation will be conducted and anthropometric measurements, then the pulmonary function tests: forced oscillation technique (FOT), whole body plethysmography, spirometry and-administration ...

Eligibility Criteria

Inclusion

  • healthy individuals, smokers and patients with chronic obstructive pulmonary disease.

Exclusion

  • healthy subjects: no history of smoking respiratory infection and disease respiratory
  • smokers and chronic obstructive pulmonary disease patients: asthma and other respiratory diseases.

Key Trial Info

Start Date :

June 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2012

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT01521572

Start Date

June 1 2011

End Date

September 1 2012

Last Update

February 2 2012

Active Locations (1)

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Laboratory biomedical instrumentation - State University of Rio de Janeiro

Rio de Janeiro, Rio de Janeiro, Brazil, 20550013