Status:

COMPLETED

Metformin Effects on Oxidative Stress Parameters in Newly Diagnosed Type 2 Diabetes Patients

Lead Sponsor:

Tehran University of Medical Sciences

Conditions:

Type 2 Diabetes Mellitus

Eligibility:

All Genders

40+ years

Phase:

NA

Brief Summary

Oxidative stress plays a key role in the pathogenesis of diabetes complications. Chronic hyperglycemia and disturbed lipid regulation commonly seen in diabetes are the main causes of this process. Des...

Eligibility Criteria

Inclusion

  • Newly diagnosed type 2 diabetes patients based on American Diabetes Association criteria for diagnosis of diabetes

Exclusion

  • No history of serious chronic illnesses of heart, lung, and kidney
  • No prior treatment with anti-diabetes medications for either diabetes or conditions associated with hyperglycemia
  • No intake of prescribed or over-the-counter vitamins C and E in the past year; - No intake of aspirin in the past year
  • No history of excessive alcohol intake in the past year

Key Trial Info

Start Date :

October 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2011

Estimated Enrollment :

108 Patients enrolled

Trial Details

Trial ID

NCT01521624

Start Date

October 1 2010

End Date

September 1 2011

Last Update

January 31 2012

Active Locations (1)

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Tehran University of Medical Sciences

Tehran, Tehran Province, Iran, 13145-784