Status:
TERMINATED
Study of Mitomycin-C Application in Laryngotracheal Stenosis
Lead Sponsor:
University of California, San Francisco
Conditions:
Laryngeal Stenosis
Subglottic Stenosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a randomized, prospective, double-blind, placebo-controlled clinical trial of the use of mitomycin-C topical application as an adjunctive treatment in the endoscopic surgical treatment of pati...
Detailed Description
Obstruction of the upper airway caused by laryngotracheal stenosis (LTS) often results in severe morbidity and even mortality. Treatment of LTS continues to present a challenge and a wide array of sur...
Eligibility Criteria
Inclusion
- Patients with laryngotracheal stenosis, including subglottic stenosis or tracheal stenosis
- Patients with disease amenable to treatment with endoscopic CO2 laser radial incisions and balloon dilation
- Age greater than or equal to 18 years
Exclusion
- Age less than 18 years
- Pregnancy
- Patients with glottic and supraglottic stenosis
- Patients with disease not amenable to treatment with endoscopic CO2 laser radial incisions and balloon dilation
- Patients with cartilaginous subglottic or tracheal stenosis
Key Trial Info
Start Date :
August 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2018
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT01523275
Start Date
August 1 2012
End Date
February 1 2018
Last Update
May 22 2019
Active Locations (1)
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1
UCSF - Voice and Swallowing Clinic
San Francisco, California, United States, 94115