Status:
UNKNOWN
68Ga-DOTATATE PET/CT in Oncogenic Osteomalacia
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Oncogenic Osteomalacia
Mesenchymal Tumor
Eligibility:
All Genders
18-70 years
Phase:
EARLY_PHASE1
Brief Summary
Oncogenic osteomalacia is rare disease predominantly caused by a small, somatostatin receptor positive mesenchymal tumor, which is frequently hidden in an unusual anatomical site and often goes undete...
Detailed Description
Oncogenic osteomalacia, or tumor-induced osteomalacia, is a rare, serious paraneoplastic syndrome. It is predominantly driven by a small, benign mesenchymal tumor. The disease is readily prompted by t...
Eligibility Criteria
Inclusion
- In suspicion of oncogenic osteomalacia according to the clinical features such as hyperphosphaturia, hypophosphatemia, low serum vitamin D3 levels, and osteomalacia. Or prior oncogenic osteomalacia patients in suspicion of relapse or with residual tumor
- At least 18 years old
- Able to provide informed consent
Exclusion
- Females planning to bear a child recently or with childbearing potential
- Renal function: serum creatinine \>3.0 mg/dL (270 μM/L)
- Liver function: any hepatic enzyme level more than 5 times upper limit of normal.
- Known severe allergy or hypersensitivity to IV radiographic contrast.
- Patients not able to enter the bore of the PET/CT scanner.
- Inability to lie still for the entire imaging time because of cough, pain, etc.
- Inability to complete the needed examinations due to severe claustrophobia, radiation phobia, etc.
- Any other medical condition that, in the opinion of the Investigator, may significantly interfere with study compliance.
Key Trial Info
Start Date :
December 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2017
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01524016
Start Date
December 1 2011
End Date
December 1 2017
Last Update
April 7 2017
Active Locations (1)
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1
Department of Nuclear Medicine, Peking Union Medical College Hopital
Beijing, China, 100730