Status:
COMPLETED
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Lead Sponsor:
The Faculty Hospital Na Bulovce
Conditions:
Acute Appendicitis
Perforated Gastroduodenal Ulcer
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appro...
Detailed Description
Introduction Infection related to surgical procedure was always considered the main cause of mortality end morbidity in surgical patients. ATB prophylaxis has become the breakthrough in surgical praxi...
Eligibility Criteria
Inclusion
- patient older \> 18 years
- Patient indicated for emergent surgery for:
- acute appendicitis / perforated gastric or duodenal ulcer / small bowel obstruction
- The patient can understand the aim of the study and sign informed consent (including language barriers)
- The diagnose is confirmed intraoperatively
Exclusion
- Refused the participation in the study and
- uninsured self-payers
- Patients with known allergy to the substance administered during the study or chronic medication contraindicated with study drug
- Pregnant or breastfeeding women
- Use of antibiotics in the last 2 weeks
- Known serious illness (heart failure, renal failure, liver failure, CNS disorders)
- Signs of infectious mononucleosis and risk of infectious endocarditis
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2011
Estimated Enrollment :
187 Patients enrolled
Trial Details
Trial ID
NCT01524081
Start Date
July 1 2008
End Date
November 1 2011
Last Update
February 8 2012
Active Locations (1)
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1
Faculty Hospital Bulovka
Prague, Czechia, 18081