Status:
COMPLETED
Cytoreduction and Intraperitoneal Chemotherapy Versus Systemic Chemotherapy in Colorectal Peritoneal Carcinomatosis
Lead Sponsor:
Uppsala University
Conditions:
Colorectal Peritoneal Carcinomatosis
Eligibility:
All Genders
18-80 years
Phase:
PHASE3
Brief Summary
The purpose of this study is to see if there is a difference in survival between two different treatment strategies for colorectal peritoneal surface disease. The control arm administered the currentl...
Eligibility Criteria
Inclusion
- Metastatic disease to the peritoneum from colon or rectum (at least two isolated sites of disease)
- verified primary tumor of adenocarcinoma of the colon or rectum
- Potential resectability as judged by the treating surgeon
- Patient is available for follow-up according to the study protocol
- Signed informed consent
Exclusion
- Extraabdominal metastases or liver metastases
- Paraaortic or other inoperable lymph node metastases
- Clear indication for surgery only (such as obstruction, bleeding or peritonitis)
- Prior treatment of either arm in the study
- Clinical or histopathological diagnosis of Peritoneal Pseudomyxoma
- Age \> 80
- Contraindications for chemotherapy
- Pregnancy or breastfeeding
- Ongoing infection
Key Trial Info
Start Date :
June 1 2003
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
49 Patients enrolled
Trial Details
Trial ID
NCT01524094
Start Date
June 1 2003
End Date
January 1 2012
Last Update
February 1 2012
Active Locations (1)
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1
Akademiska Sjukhuset (Uppsala University Hospital)
Uppsala, Sweden, SE-751 85