Status:
COMPLETED
Effect of Chronic Consumption of a Cranberry Beverage on Inflammation and Oxidative Stress
Lead Sponsor:
Tufts University
Collaborating Sponsors:
Washington State University
Ocean Spray, Inc.
Conditions:
Inflammation
Eligibility:
All Genders
30-70 years
Phase:
NA
Brief Summary
The objective of this randomized, double-blind, placebo-controlled, parallel-design clinical trial is to investigate the potential antioxidant benefits of a cranberry beverage. The investigators hypot...
Eligibility Criteria
Inclusion
- Men \& women, aged 30-70 years
- BMI 27-34.9 kg/m2
- waist:hip ratio \> 0.8 for women and \> 0.9 for men
Exclusion
- Cigarette smoking and/or nicotine replacement use within last 6 months
- Individuals taking estrogen or testosterone
- Use of cholesterol-lowering medications
- Use of blood pressure-lowering medications
- Regular use (\> 1x/wk) of any stomach acid-lowering medications or laxatives (including fiber supplements)
- Cardiovascular (heart) disease
- Gastrointestinal disease
- Kidney disease
- Endocrine disease: including diabetes, untreated thyroid disease
- Rheumatoid arthritis
- Immune deficiency conditions
- Active treatment for any type of cancer, except basal cell carcinoma, within 1 year prior to study admission
- Systolic blood pressure \> 139 mmHg and/or diastolic blood pressure \> 89 mmHg
- Regular use of systemic steroids, oral or injectable
- Regular daily intake of ≥ 2 alcoholic drinks
- Infrequent (\< 3/week) or excessive (\> 3/d) number of regular bowel movements
- Gain or loss of ≥ 5% of body weight in the last 6 months
- Pregnancy
- Strict vegetarians
- No dietary supplements, including those containing any vitamins, minerals, herbs, plant concentrates (including garlic, gingko, St. John's wort) homeopathic remedies, probiotics, or fish oil (including cod liver oil), for one month prior to study admission
Key Trial Info
Start Date :
February 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2013
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT01527617
Start Date
February 1 2012
End Date
February 1 2013
Last Update
June 2 2016
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University
Boston, Massachusetts, United States, 02111
2
Washington State University
Pullman, Washington, United States, 99164