Status:
COMPLETED
Effect of Midazolam on White-coat Hypertensive Dental Patients
Lead Sponsor:
Okayama University
Conditions:
Transient Hypertension
Eligibility:
All Genders
20-64 years
Phase:
NA
Brief Summary
Intravenous sedation was used for dealing with transient hypertension, so-called white-coat hypertension, before dental treatment. Midazolam used as a sedative also has antianxiety effect, and the mec...
Eligibility Criteria
Inclusion
- SBP\>=140mmHg or DBP\>=90mmHg measuring when the patient sits on dental chair and has settled down for 5 minutes among dental outpatients scheduling intravenous sedation with American Society of Anesthesiologists physical status I or II.
Exclusion
- Uncontrolled or unstable hypertension
- Secondary hypertension such as hyperthyroidism and pheochromocytoma
- Taking sympathomimetic drugs
- Contraindication of midazolam such as myasthenia gravis and acute narrow-angle glaucoma
- A pregnant woman or during lactation period
- Psychiatric disorder such as schizophrenia
- Not having intelligence enough to read, understand and write a Japanese version of STAI
- Judged unsuitable by a researcher
Key Trial Info
Start Date :
October 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2012
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01528371
Start Date
October 1 2010
End Date
July 1 2012
Last Update
October 3 2012
Active Locations (1)
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1
Department of Dental Anesthesiology and Special Care Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Okayama, Japan