Status:
RECRUITING
Genetics of Reproductive Disorders (Including Kallmann Syndrome) and Cleft Lip and/or Palate
Lead Sponsor:
Centre Hospitalier Universitaire Vaudois
Collaborating Sponsors:
Swiss National Science Foundation
Conditions:
Kallmann Syndrome
Hypogonadotropic Hypogonadism
Eligibility:
All Genders
Brief Summary
The purpose of this study is to explore the genetic basis of reproductive disorders and cleft lip and/or palate.
Detailed Description
The World Health Organization estimates approximately 10% of couples experience some sort of infertility problem. In humans, puberty is the process through which we develop reproductive capacity. Th...
Eligibility Criteria
Inclusion Criteria:(any of the following conditions)
- hypogonadotropic hypogonadism
- Kallmann syndrome
- adult-onset hypogonadotropic hypogonadism
- hypothalamic amenorrhea
- polycystic ovarian syndrome
- primary gonadal failure
- precocious puberty
- cleft lip/palate
- family members of the above groups
Exclusion Criteria:
- acute illness/hospitalization
- pituitary tumors
- iron overload (hemochromatosis)
- infiltrative diseases (sarcoidosis)
- chronic alcohol abuse
- illicit drug use
- anabolic steroid abuse
Key Trial Info
Start Date :
March 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2030
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT01601171
Start Date
March 1 2012
End Date
March 1 2030
Last Update
June 21 2022
Active Locations (1)
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1
Centre Hospitalier Universitaire Vaudois (CHUV)
Lausanne, Canton of Vaud, Switzerland, 1011