Status:

COMPLETED

Peripheral Blood DNA Methylation Markers for the Early Detection of Colorectal Carcinoma in the Egyptian Population

Lead Sponsor:

Cairo University

Collaborating Sponsors:

National Cancer Institute (NCI)

science and technology development fund, Egypt

Conditions:

Colorectal Neoplasms

Adenoma

Eligibility:

All Genders

18-85 years

Brief Summary

The incidence of colorectal cancer (CRC) is on the rise on a global scale. The number of cancer-related deaths related to CRC is also rising to an alarming level. This picture is similarly seen in Egy...

Eligibility Criteria

Inclusion

  • Patients undergoing colonoscopy as part of their clinical care or part of screening program.
  • Complete endoscopic examination (up to the caecum)
  • Adequate colonic preparation

Exclusion

  • \- Incomplete colonoscopic examination due to technical causes e.g. difficult colonoscopy, patient intolerance (N.B. a neoplastic mass causing lumen stenosis will not be excluded.)
  • Poor colonic preparation obscuring adequate mucosal examination.
  • Patients who have received any treatment for CRC and/or adenomas.
  • Patients with known malignancy elsewhere (i.e. non-colorectal malignancy)

Key Trial Info

Start Date :

December 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2015

Estimated Enrollment :

316 Patients enrolled

Trial Details

Trial ID

NCT01793207

Start Date

December 1 2012

End Date

March 1 2015

Last Update

May 6 2015

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Kar-Alaini hospital (Cairo Univeristy hospital)

Cairo, Egypt

2

National cancer institute

Cairo, Egypt