Status:
COMPLETED
Influence of Muscle Strength on the Energy Cost of Walking in Obese Subjects
Lead Sponsor:
Centre Hospitalier Universitaire de la Réunion
Collaborating Sponsors:
Universite de La Reunion
Conditions:
Obesity
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
The purpose of this study is to evaluate the efficacy of 2 physical exercise training programs, with a supplementation in fruits and vegetables, on energy cost of walking. 60 subjects will be randomiz...
Detailed Description
Background: in Reunion Island in 2000, the REDIA study showed a prevalence of obesity among women and men of 20% and 10%, respectively. Obesity is associated with several diseases, including diabetes ...
Eligibility Criteria
Inclusion
- Men and women
- 18-40 years old
- 30 ≤ BMI ≤40 kg / m²
- sedentary
- considered clinically stable
- able to rehabilitation training
- having signed an informed consent
- without professional activity
Exclusion
- blood glucose ≥ 1.26 g / l
- HbA1c ≥ 6.5%
- severe hypertension (Systolic Blood Pressure (SBP) ≥ 180 mmHg and / or Diastolic Blood Pressure (DBP) ≥ 110 mmHg)
- hypertension (≥140/90 mmHg) untreated or treated by beta blocker or calcium blocker
- absolute and relative contraindication to the maximal exercise test (ACC / American Heart Association 2002) and / or physical training
- inability to achieve the maximum exercise test and / or the metabolic exercise test by indirect calorimeter
- uncompensated cardiovascular and / or respiratory disease revealed by exercise test
- pacemaker or defibrillator
- recent cardiovascular events (heart failure, treated by positive inotropic drugs, angioplasty within the last 10 days, cardiac surgery within the last 3 months, valvular disease requiring surgical correction, evolving myopericarditis, severe ventricular arrhythmias non stabilized under treatment)
- known and documented myopathy
- cancer
- acute and chronic inflammatory disease
- end stage renal disease
- digestive system operation
- treated by corticoids, thyroid hormone, antidepressant or neuroleptics
- pregnancy
- mental deficiency that prevents the understanding of informed consent and protocol
- participation to another research protocol
- attendance in the previous month to a program of rehabilitation training or a diet
- associated evolutionary disease causing significant impairment of general condition.
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
59 Patients enrolled
Trial Details
Trial ID
NCT01794377
Start Date
February 1 2013
End Date
December 1 2013
Last Update
July 25 2014
Active Locations (1)
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1
CHU de La Réunion
Saint-Pierre, La Réunion, France, 97448