Status:

COMPLETED

The Molecular Pathogenesis of Late-onset Fuchs' Endothelial Corneal Dystrophy

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Collaborating Sponsors:

Fund for Scientific Research, Flanders, Belgium

Funds for Research in Ophthalmology, Belgium

Conditions:

Fuchs' Endothelial Dystrophy

Eligibility:

All Genders

Brief Summary

The purpose of this study is to gain further insights into the molecular pathogenesis of Fuchs' endothelial corneal dystrophy (FECD), to identify targets for potential specific drug therapy.

Eligibility Criteria

Inclusion

  • FECD
  • normal corneas (including enucleations for uveal melanoma)
  • non-FECD oedematous corneas

Exclusion

  • prior irradiation therapy for uveal melanoma
  • corneal extension of uveal melanoma

Key Trial Info

Start Date :

October 1 2012

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 13 2017

Estimated Enrollment :

460 Patients enrolled

Trial Details

Trial ID

NCT01795001

Start Date

October 1 2012

End Date

September 13 2017

Last Update

May 24 2018

Active Locations (1)

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Department of Translational Cell and Tissue Research - campus Sint-Raf - UZ Leuven

Leuven, Belgium, 3000