Status:
COMPLETED
Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis
Lead Sponsor:
The Cleveland Clinic
Collaborating Sponsors:
GE Healthcare
Conditions:
Takayasu's Arteritis
Giant Cell Arteritis
Eligibility:
All Genders
18-100 years
Brief Summary
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis ...
Detailed Description
Takayasu's arteritis and Giant Cell arteritis are chronic, relapsing diseases of the large arteries which can lead to significant narrowing of the arteries through episodes of inflammation within the ...
Eligibility Criteria
Inclusion
- Male and female patients \>18 years
- Diagnosis of Takayasu's arteritis or giant cell arteritis
- Suspicion of common carotid involvement on the basis of physical examination (cervical bruit), carotidynia, documented CCA involvement on an imaging study (MRA, CTA, or ultrasound), or documented upper extremity large vessel involvement on an imaging study (MRA or CTA or ultrasound).
- Ability to provide informed consent
Exclusion
- Prior stroke, carotid surgery or angioplasty
- Pregnant (or trying to become pregnant)
- Nursing
- Known or suspected cardiac shunt
- Documented hypersensitivity to the contrast agent
- Severe pulmonary hypertension or unstable cardiopulmonary conditions (acute myocardial infarction, acute coronary artery syndromes, worsening or unstable congestive heart failure, serious ventricular arrhythmias, or respiratory failure)
Key Trial Info
Start Date :
August 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2014
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT01795456
Start Date
August 1 2010
End Date
January 1 2014
Last Update
January 27 2017
Active Locations (1)
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1
Cleveland Clinic Main Campus, Section of Vascular Medicine
Cleveland, Ohio, United States, 44011