Status:
COMPLETED
Home Treatment of Acute Pancreatitis
Lead Sponsor:
Bezmialem Vakif University
Conditions:
Acute Pancreatitis
Eligibility:
All Genders
18+ years
Brief Summary
Acute pancreatitis (AP) is considered a disease requiring in-hospital treatment. We studied the feasibility of home management in AP.The aim of study was to compare 30 day readmission rates in patient...
Detailed Description
Between 11/11-5/12, 84 patients with mild NAAP were randomized to home or hospital groups after a short (≤24 hours) hospital stay. AP was defined as ≥2 or more of the following: characteristic abdomin...
Eligibility Criteria
Inclusion
- Diagnosis of AP based on 2 out of 3 findings: characteristic abdominal pain, amylase and/or lipase levels ≥3 times the upper limit of normal, and/or abdominal imaging demonstrating changes of acute pancreatitis
- Presentation within 48 hours of symptom onset
- Imrie's scores of ≤5 and HAP score ≤2 within 24 hours of presentation to the hospital
- Lack of hemoconcentration (hematocrit ≥44%) on presentation since hemoconcentration has been shown to be a risk factor for pancreatic necrosis.
Exclusion
- The presence of organ failure by the Atlanta criteria on the first day of presentation
- The presence of clinical signs and/or symptoms of sepsis
- Alcoholic acute pancreatitis
- A history of abdominal imaging demonstrating a dilated pancreatic duct and/or pancreatic calcifications
- Coagulopathy (international normalized ratio \>1, and/or platelet count \<50,000/mm3
- Comorbidities requiring hospitalization regardless of the presence of AP e.g. acute myocardial infarction, malignancy, cirrhosis, chronic kidney disease, and chronic pulmonary disease)
Key Trial Info
Start Date :
November 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT01796652
Start Date
November 1 2011
End Date
June 1 2012
Last Update
February 22 2013
Active Locations (1)
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1
Bezmialem Vakıf University Hospital, Gastroenterology Clinic
Istanbul, Turkey (Türkiye), 34093