Status:
TERMINATED
Oestradiol Pre-treatment in an Ultrashort Flare GnRH Agonist/GnRH Antagonist Protocol in Poor Responders Undergoing IVF
Lead Sponsor:
National and Kapodistrian University of Athens
Conditions:
Infertility
Eligibility:
FEMALE
25-44 years
Phase:
PHASE2
PHASE3
Brief Summary
To evaluate the effect of oestradiol pre-treatment in a combined ultrashort flare GnRH agonist /GnRH antagonist protocol
Detailed Description
The combined ultrashort flare GnRH agonist /GnRH antagonist protocol during COH cycle resulted in a significantly higher clinical pregnancy rate in patients with poor embryo quality, with repeated IVF...
Eligibility Criteria
Inclusion
- Patients with poor or no response in previous COH for IVF cycles
- Patients with AMH \< 1 and/or FSH \>12
- Poor quality of embryos in previous cycles
- Age of patients up to 44 years
Exclusion
- Patients with normal ovarian reserve
- Patients with sonographically detected hydrosalpinges
- Presence of intramural fibroid distorting the endometrial cavity or submucous myoma or Asherman's syndrome
- Women with thrombofilia disorders
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2015
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT01798836
Start Date
February 1 2013
End Date
February 1 2015
Last Update
August 6 2015
Active Locations (1)
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1
Assisted Reproduction Unit, 3rd Department of Obstetrics and Gynecology. Attikon University Hospital
Athens, Attica, Greece, 12642