Status:
COMPLETED
Micropulse Laser for Geographic Atrophy
Lead Sponsor:
Institut de la Macula y la Retina
Conditions:
Geographic Atrophy
Age-related Macular Degeneration
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
Geographic atrophy (GA) causes the loss of the retinal pigment epithelium (RPE) cells in broad areas of the retina. The application of subthreshold micropulse laser spots in healthy RPE in the vicinit...
Eligibility Criteria
Inclusion
- GA \> 0.5 disk areas secondary to AMD in both eyes
- 50 years or older
- The periphery of the atrophic lesions must demonstrate increased autofluorescence
- Best corrected visual acuity between 20/20 and 20/400 inclusive
- Clear ocular media
- Ability to provide informed consent and attend all study visits
Exclusion
- GA secondary to other causes aside from AMD
- Evidence of choroidal neovascularization in either eye
- Any prior treatment for AMD, aside from antioxidants
- Any other ocular condition that would progress in the study period and confound visual acuity assessment
- Any ocular or systemic medication known to be toxic to the lens, retina or optic nerve
- Presence of idiopathic or autoimmune-associated uveitis
- Any intraocular surgery 3 months of entry
- Any prior thermal laser in the macula
- History of vitrectomy, filtering surgery, corneal transplant or retinal detachment surgery
- Previous therapeutic radiation in the ocular region in either eye
- Any treatment with an investigational agent in the previous 60 days before study entry
Key Trial Info
Start Date :
August 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 27 2013
Estimated Enrollment :
11 Patients enrolled
Trial Details
Trial ID
NCT01799564
Start Date
August 1 2012
End Date
November 27 2013
Last Update
September 18 2019
Active Locations (1)
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1
Institut de la màcula i de la retina
Barcelona, Spain, 08022