Status:
COMPLETED
Effects of Aerobic Training on Exercise Capacity in Patients With Cirrhosis
Lead Sponsor:
University of Alberta
Conditions:
Cirrhosis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Cirrhosis is associated with a reduction in muscle mass and exercise capacity. This has an impact or morbidity and mortality. Regular aerobic exercise training is a proven effective therapy to improve...
Eligibility Criteria
Inclusion
- Age ≥18 and ≤70 years
- Cirrhosis
- Child Pugh class A or B
- If required, primary or secondary variceal prophylaxis in place
Exclusion
- Post-liver transplantation
- Hepatocellular carcinoma
- Active non-Hepatocellular carcinoma malignancy
- Significant cardiac disease - ejection fraction \<60% or known coronary artery disease
- Oxygen saturation at rest \<95%
- Known myopathy
- Hemoglobin (\<100 g/L)
- Chronic renal failure on dialysis
- Physical impairment making it impossible to ride an exercise bike or treadmill
- Orthopedic abnormality preventing exercise training
- HIV infection
- Patient unwilling to consent to study
Key Trial Info
Start Date :
February 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2013
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01799785
Start Date
February 1 2013
End Date
July 1 2013
Last Update
October 9 2013
Active Locations (1)
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1
University of Alberta, Mazankowski Heart Institute
Edmonton, Alberta, Canada, T6G2B1